Know when treatment needs a pause or you need help.

Which offers need a pause?

As of September 2026, a prescription drug could not be supplied under U.S. law without a licensed clinician’s order.

FDA’s checklist flags missing assessment, no clinician available for later questions, doubtful pharmacy names and damaged packaging.

As of September 2026, a compounded preparation described as FDA-approved was making a false approval claim.

FDA received reports of mistakes when people measured pharmacy-made semaglutide. Some reports involved hospital care.

If the medicine information is unclear, ask the prescriber or pharmacist to explain it. A web calculator is not a substitute for their explanation.

What if the delivery arrives warm?

FDA advises against using a GLP-1 injection if it is warm on arrival or has lacked adequate cooling. That can affect the drug’s quality.

The hormone GLP-1 sends a chemical message within the body, helping with fullness and blood sugar.

Contact the dispensing pharmacy about the delivery and the product’s storage instructions. Keep the packaging details for that conversation.

Which symptoms need urgent help?

Severe allergy symptoms can include problems breathing and swelling affecting the tongue or face. Such a reaction can threaten life.

For severe allergic-reaction symptoms, emergency care is the advice from MedlinePlus, the U.S. health-information service.

The official semaglutide and tirzepatide instructions warn about belly pain that lasts or is severe, sometimes reaching the back. This can be a sign of painful swelling in the pancreas, an organ inside the belly.

Seek prompt medical attention for those symptoms. Do not use this page to diagnose the cause.

Patients can send FDA a medicine-problem report using MedWatch. There is no charge.

A report to FDA is separate from getting medical care for the problem.